Louisiana Highway 40 (LA 40) is a state highway located in southeastern Louisiana. It runs 53.11 miles (85.47 km) in an east–west direction from LA 43 south of Montpelier to LA 41 in Bush. The route travels through the rural area between the parallel corridors of U.S. Highway 190 (US 190) and LA 21 to the south and LA 16 to the north. It connects several small population centers in Tangipahoa and St. Tammany parishes. These include the town of Independence, the village of Folsom, and the unincorporated communities of Loranger and Bush. LA 40 also connects Independence with Interstate 55 (I-55), the area's primary route to the New Orleans area. Further east, the highway provides access to the Global Wildlife Center, a popular wildlife and game preserve located west of Folsom.