Louisiana Highway 43 (LA 43) is a state highway located in southeastern Louisiana. It runs 44.38 miles (71.42 km) in a north–south direction from LA 42 west of Springfield to the Mississippi state line north of Easleyville, where it continues as (MS 568). A primarily rural route, LA 43 connects four small municipalities in Livingston and St. Helena parishes, including Springfield, Albany, Montpelier, and Greensburg. The latter is also the seat of St. Helena Parish. LA 43 was designated in the 1955 Louisiana Highway renumbering from portions of former and .