New York State Route 69 (NY 69) is a state highway extending for 57.42 miles (92.41 km) across the central portion of the U.S. state of New York. The western terminus of the route is at NY 104 in the Oswego County village of Mexico. The eastern terminus is at NY 5A in the Oneida County village of Yorkville, just west of Utica. In between, NY 69 serves the city of Rome.