About: Oligomer restriction

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Oligomer Restriction (abbreviated OR) is a procedure to detect an altered DNA sequence in a genome. A labeled oligonucleotide probe is hybridized to a target DNA, and then treated with a restriction enzyme. If the probe exactly matches the target, the restriction enzyme will cleave the probe, changing its size. If, however, the target DNA does not exactly match the probe, the restriction enzyme will have no effect on the length of the probe. The OR technique, now rarely performed, was closely associated with the development of the popular polymerase chain reaction (PCR) method.

Attributes	Values
rdf:type	anatomical structure yago:WikicatLaboratoryTechniques yago:WikicatMolecularBiologyTechniques yago:Ability105616246 yago:Abstraction100002137 yago:Cognition100023271 yago:Know-how105616786 yago:Method105660268 yago:PsychologicalFeature100023100 yago:Technique105665146
rdfs:label	Oligomer restriction (en)
rdfs:comment	Oligomer Restriction (abbreviated OR) is a procedure to detect an altered DNA sequence in a genome. A labeled oligonucleotide probe is hybridized to a target DNA, and then treated with a restriction enzyme. If the probe exactly matches the target, the restriction enzyme will cleave the probe, changing its size. If, however, the target DNA does not exactly match the probe, the restriction enzyme will have no effect on the length of the probe. The OR technique, now rarely performed, was closely associated with the development of the popular polymerase chain reaction (PCR) method. (en)
foaf:depiction
dcterms:subject	DNA profiling techniques Molecular biology Molecular biology techniques Laboratory techniques
Wikipage page ID	16784189 (xsd:integer)
Wikipage revision ID	1010840630 (xsd:integer)
Link from a Wikipage to another Wikipage	DNA profiling techniques DNA polymerase DNA replication Polymerase chain reaction Nucleic acid hybridization Gel electrophoresis Genome Nature (journal) Oligonucleotide Emeryville, California Frederick Sanger Genetic polymorphism Molecular biology Molecular biology techniques Restriction enzyme Hybridization probe Laboratory techniques Kary Mullis Human β-globin locus Cetus Corporation Chain reaction Restriction Fragment Length Polymorphism History of PCR Southern blot Chain termination method Sickle Cell Anemia Recognition site Allele specific oligonucleotide
sameAs	Oligomer restriction Oligomer restriction Oligomer restriction Oligomer restriction
dbp:wikiPageUsesTemplate	dbt:Reflist
thumbnail	wiki-commons:Special:FilePath/ORDemo.gif?width=300
has abstract	Oligomer Restriction (abbreviated OR) is a procedure to detect an altered DNA sequence in a genome. A labeled oligonucleotide probe is hybridized to a target DNA, and then treated with a restriction enzyme. If the probe exactly matches the target, the restriction enzyme will cleave the probe, changing its size. If, however, the target DNA does not exactly match the probe, the restriction enzyme will have no effect on the length of the probe. The OR technique, now rarely performed, was closely associated with the development of the popular polymerase chain reaction (PCR) method. (en)
gold:hypernym	Procedure
prov:wasDerivedFrom	wikipedia-en:Oligomer_restriction?oldid=1010840630&ns=0
page length (characters) of wiki page	7456 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Oligomer_restriction
is Link from a Wikipage to another Wikipage of	Allele-specific oligonucleotide History of polymerase chain reaction Restriction fragment length polymorphism Oligomer Restriction
is Wikipage redirect of	Oligomer Restriction
is foaf:primaryTopic of	wikipedia-en:Oligomer_restriction

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