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Phytohaemagglutinin (PHA, or phytohemagglutinin) is a lectin found in plants, especially certain legumes. PHA actually consists of two closely related proteins, called leucoagglutinin (PHA-L) and PHA-E. These proteins cause blood cells to clump together. PHA-E cause erythrocytes (red blood cells) to clump. PHA-L causes leukocytes (white blood cells) to clump. Phytohaemagglutinin has carbohydrate-binding specificity for a complex oligosaccharide containinggalactose, N-acetylglucosamine, and mannose.

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rdfs:label
  • Phytohämagglutinin (de)
  • Fitohemaglutinina (es)
  • Fitoemoagglutinina (it)
  • Phytohémagglutinine (fr)
  • Fytohemagglutinine (nl)
  • Phytohaemagglutinin (en)
  • Фитогемагглютинин (ru)
  • 植物血凝素 (zh)
rdfs:comment
  • Phytohämagglutinin (PHA) ist ein Gemisch von zwei Proteinen aus der Gruppe der Lektine, (für Erythrozyten-bindend) und (für Leukozyten-bindend). (de)
  • La phytohémagglutinine, ou phasine (PHA) est une lectine présente chez les plantes, particulièrement chez les légumineuses, notamment les haricots. Cette substance a de nombreux effets physiologiques et est utile en recherche médicale. À haute dose, c'est une toxine. (fr)
  • La fitoemoagglutinina (PHA) è una lectina presente nei semi di alcune leguminose come il fagiolo. La PHA in realtà consiste di due proteine strettamente correlate, chiamate PHA-L e PHA-E. Le lettere E e L indicano che queste proteine sono in grado di agglutinare rispettivamente gli eritrociti e i leucociti. La fitoemoagglutinina presenta una specificità di legame per i carboidrati, in particolare per un complesso oligosaccaridico contenente galattosio, N-acetilglucosammina e mannosio. (it)
  • 植物血凝素（Phytohaemagglutinin，PHA）是一种存在于植物中的，多存在于在某些豆类中。PHA实际上由两种密切相关的蛋白质组成，称为白细胞凝集素（PHA-L）和红细胞凝集素（PHA-E）。这些蛋白质导致血细胞聚集在一起。PHA-E 会导致红细胞凝集。PHA-L 会导致白细胞凝集。 植物血凝素为低聚糖（由D一甘露糖、衍生物所构成）与蛋白质的复合物，属于高分子糖蛋白类，存在于一些豆类种子中，对血细胞有一定凝集作用，故名。 (zh)
  • Фитогемагглютинин (ФГА, PHA) — белок-лектин растительного происхождения, или легумин, получаемый из красной обыкновенной фасоли Phaseolus vulgaris. ФГА включает два белка: лейкоагглютинин L-ФГА (PHA-L), агглютинирующий лейкоциты, и R-ФГА (PHA-E), агглютинирующий эритроциты. Фитогемагглютинин специфически связывает сложные олигосахариды, содержащие остатки галактозы, N-ацетилглюкозамина и маннозы. Открыт американским учёным-онкологом Питером Ноуэллом в 1960 году. (ru)
  • La fitohemaglutinina (conocida como PHA por la abreviación de Phytohaemagglutinin) es una lectina ampliamente distribuida entre la legumbres y en algunas oleaginosas incluida la soja Glycine max. Las lectinas son proteínas que reconocen carbohidratos y se caracterizan por su habilidad para combinarse con receptores de membrana de gram +. (es)
  • Phytohaemagglutinin (PHA, or phytohemagglutinin) is a lectin found in plants, especially certain legumes. PHA actually consists of two closely related proteins, called leucoagglutinin (PHA-L) and PHA-E. These proteins cause blood cells to clump together. PHA-E cause erythrocytes (red blood cells) to clump. PHA-L causes leukocytes (white blood cells) to clump. Phytohaemagglutinin has carbohydrate-binding specificity for a complex oligosaccharide containinggalactose, N-acetylglucosamine, and mannose. (en)
  • Fytohemagglutinine (PHA), vroeger ook wel fasine genoemd, is een lectine die aangetroffen wordt in planten. De stof wordt gebruikt in medisch onderzoek als activator van T-lymfocyten. Fytohemagglutinine wordt in de hoogste concentratie aangetroffen in rode nierbonen (Phaseolus vulgaris). Ook in rauwe peulvruchten en aardappelen komt het voor. De planten, waaraan deze producten groeien, produceren deze stof om diervraat tegen te gaan. In hoge doses is het een gif. PHA bestaat uit twee gerelateerde proteïnes, en . (nl)
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  • Legume lectin domain (en)
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