Dasho Sherub Gyeltshen (Dzongkha: དྲག་ཤོས་ཤེས་རབ་རྒྱལ་མཚན།; born c. 1955) is a Bhutanese politician who served as the Minister for Home and Cultural Affairs from November 2018 to 6 May 2021 when he resigned as the Minister for Home and Cultural Affairs. He was a member of the National Assembly of Bhutan from October 2018 to May 6, 2021.