The Wistar Institute (/ˈwɪstɑːr/) is an independent, nonprofit research institution in biomedical science, with special expertise in oncology, immunology, infectious disease and vaccine research. Located on the campus of the University of Pennsylvania, Wistar was founded in 1892 as America's first nonprofit institution solely focused on biomedical research and training. The institute has historic and contemporary ties with the university, reflected in research collaboration and shared access to facilities.