José E. Romero, Sr. (born José Romero y Muñoz; 3 March 1897 – 23 October 1978), commonly known as José E. Romero, was a statesman and diplomat from the Philippines. He represented Negros Oriental's Second District and was Majority Floor Leader during the Ninth and Tenth Philippine Legislatures and the First and Second National Assemblies of the Philippines. He was senator-elect of the First Congress of the Philippines and later became the first Philippine ambassador to the United Kingdom and Secretary of Education.