Maurilio Castillo (born 1 December 1962) is a Mexican male former long-distance runner who specialised in the marathon. He represented his country at the 1991 World Championships in Athletics and finished seventh there. He holds a personal best of 2:10:47 hours set when he finished third at the Tokyo International Marathon. He was the 1992 winner at the Central American and Caribbean Cross Country Championships. Castillo also competed at the 1995 Pan American Games.