The National Tainan First Senior High School (Chinese: 國立臺南第一高級中學; pinyin: Guólì Táinán Dìyī Gāojí Zhōngxué) is a public senior high school in East District, Tainan, Taiwan. It was established in 1922 and is considered one of the most prestigious high schools in Taiwan, usually only accepting students who rank in the top 3 percentage of the Taiwan Basic Scholastic Test.