Wetshotsile Joseph Seremane (born 26 August 1938) is a former South African politician and federal chairperson of the country's main opposition party, the Democratic Alliance (DA). Seremane started his career as a school teacher in Bekkersdal in the Gauteng province of South Africa, until he was barred from teaching due to his involvement in politics. He was a political prisoner on Robben Island from 1963 to 1969, before being deported by the apartheid government to the then black homeland of Bophuthatswana. He was further detained without trial from 1976 to 1978, and several times between 1982 and 1984.