USS Indianola was a casemate ironclad that served as a river gunboat for the Union Navy during the American Civil War. A side-wheel steamer also equipped with two screw propellers, Indianola was built in Cincinnati, Ohio in 1862 by Joseph Brown before being taken by Union authorities while still incomplete, in response to a perceived Confederate threat to Cincinnati. After completion, the vessel briefly served on the Mississippi River and the Yazoo River before being sent downstream of Vicksburg, Mississippi in February 1863, to support the naval ram USS Queen of the West, which was operating against Confederate shipping.